Scientific Understanding Of Antibodies As ‘Miasms’- A Full Text Of Facebook Discussions

This is full text of conversations regarding ‘miasms’ on ‘total cure group’ and my wall

Chandran Nambiar K C:-

I was pointing to the pathogenic role of antibodies. We already know a lot about the havoc antibodies create by their off-target actions up on biological molecules. Most of the chronic effects of infectious diseases are understood to be caused by the antibodies generated. And also those hundreds of serious auto immune diseases, where antibodies are the real pathogenic agents. Hahnemann defined miasms as ‘chronic disease dispositions’ created by ‘infectious diseases. Only way by which acute infectious diseases can cause life-long chronic disease dispositions are through the existence of antibodies. That is why I say ‘miasms’ are ‘chronic disease dispositions’ caused by ‘antibodies’ formed against infectious diseases. The belief that antibodies have only a ‘protective’ role is not right. For example, the chronic crippling pains remaining life long after chikunguniya is caused by antibodies. Can we say antibodies have only protective role here? We know various chronic diseases dispositions caused by vaccinations, which we call vaccinosis, which are actually pathogenic actions of antibodies. I have also pointed earlier to streptococcus antibodies causing cardiac problems and kidney problems. There are already studies regarding the role of antibodies in causing diabetes. Still would anybody say antibodies have “only protective role”?

Now coming to the question “how antibodies can they produce diseases”. Exactly, antibodies are globulin proteins subjected to molecular imprinting by bacterial/viral toxins, which are called antigens. The antibody has a unique part known as “paratope” (a structure analogous to a lock) on it, that is specific for one particular “epitope” (similarly analogous to a key) on an antigen, allowing these two structures to bind together with precision. These “paratopes” of antibodies are the result of molecular imprinting. Using this binding mechanism, an antibody can tag a microbe or an infected cell for attack by other parts of the immune system, or can neutralize its target directly (for example, by blocking a part of a microbe that is essential for its invasion and survival). Apart from that, these antibodies can bind to native biological molecules having structural groups similar in configuration to the “epitope” of its antigens. This can be compared to the damaging of a lock by inserting a wrong key with some similarity to original key. Such bindings cause molecular errors, which cause various pathological conditions. This is the real molecular mechanism by which antibodies act as “disease causing agents”. You can learn this phenomenon better if you update your immunology and biochemistry. I am saying pure scientific facts, not my inventions.

Chandran Nambiar K C:-

Fundamental therapeutic law of homeopathy is “Similia Similibu Curentur”, and “totality of symptoms” presented by the patient is the most reliable guide in selecting most appropriate similimum. When following so called ‘miasmatic analysis’, ‘flow charts’ ‘genetic interpretations’, ’embriyonic layers’ and such other ‘pseudo-scientific and somewhat ambiguous ‘principles and methods’ propagated by different people, never forget SIMILIA SIMILIBUS CURENTUR. Remember, that is real homeopathy!

Avtar Singh Mavi:-

Firmness of a theory can only be backed up by the results which can be obtained by the use of that theory. Similia Siilibus Currentur was theory but during Hahnemann or after him whoever used it properly came to know that it gave good results.. Adding big names of physics, chemistry does not prove that a theory is scientific, it has to give results in cases of multiple sclerosis, demyelinating diseases, genetic mutations, cancers, AIDS and other autoimmune disorders- that was why Hahnemann discovered homoeopathy. Embryonic layers is what Herings law says, if u can understand the relation between its postulates and embryology. That is scientific. Gentic interpretation is what hahnemann have told us to do of a patient- read aphorism 5 and 81- where he have clearly told about the genetics of a patient and how it acts in creating disease. Thats scientific. Miasmatic analysis, which hahnemann has described as keystone in curing incurable cases and without which, he said, homoeopathy wont work (refer Chronic Diseases). If u want to follow Hahnemann’s Theories and Laws then follow all or follow none…..and sorry Dr. Chandran but the above said “unscientific” or ‘pseudo-scientific’ theories are only the scientific one, if you can 1st study embroyology, physiology, pathology(which are scientific) thoroughly and apply it the the thoeries of Dr. Hahnemann. and above all application of all these theories are giving wonderful results in above mentioned cases, not only by one or two persons but by hundreds…..that itself shows scientificness of these theories . That is Real and Right Homoeopathy!

Chandrakant Pillai:

yes sir,as long as we give CURE to the patient without any harm…..that’s Real and Right HOMOEOPATHY.

Chandran Nambiar K C:

‎@Avtar Singh Mavi: Sir, everybody would claim that their “theories are only the scientific one”. When you claim “application of all these theories are giving wonderful results”, kindly do not forget that all homeopaths who genuinely follo…w “similia similibus curentur” are also getting ‘wonderful results’. When you say only your method is “Real and Right Homoeopathy”, do you mean all those homeopaths who do not follow the “principles and methods” propagated by you are not practicing “Real and Right Homoeopathy”? Sorry sir, I think it is a far extended claim.

DrPravin Dhole:

Dr chandran sir : what is the importance of six modification in totality of symptoms ,? why the charector of pain changes? what is impotance of location? why the extension occurs ? why the modalities forms? why the concommitants present ?

Chandran Nambiar K C:

‎@Avtar Singh Mavi: Sir, since you kindly asked me to “read aphorism 5 and 81- where he have clearly told about the genetics of a patient and how it acts in creating disease’ I think it would not be inappropriate to quote those parts of ORG…ANON here. I would like to know how could you relate these statements of the master with modern GENETICS? Where did he “clearly told about the genetics”?

Organon : Aphorism 5: “Useful to the physician in assisting him to cure are the particulars of the most probable exciting cause of the acute disease, as also the most significant points in the whole history of the chronic disease, to enable him to discover its fundamental cause, which is generally due to a chronic miasm. In these investigations, the ascertainable physical constitution of the patient (especially when the disease is chronic), his moral and intellectual character, his occupation, mode of living and habits, his social and domestic relations, his age, sexual function, etc., are to be taken into consideration.”

Aphorism 81:”The fact that this extremely ancient infecting agent has gradually passed, in some hundreds of generations, through many millions of human organisms and has thus attained an incredible development, renders it in some measure conceivable how it can now display such innumerable morbid forms in the great family of mankind, particularly when we consider what a number of circumstances contribute to the production of these great varieties of chronic diseases (secondary symptoms of psora), besides the indescribable diversity of men in respect of their congenital corporeal constitutions, so that it is no wonder if such a variety of injurious agencies, acting from within and from without and sometimes continually, on such a variety of organisms permeated with the psoric miasm, should produce an innumerable variety of defects, injuries, derangements and sufferings, which have hitherto been treated of in the old pathological works, under a number of special names, as diseases of an independent character”See More

DrPravin Dhole:

throbbing pain never changing in dull acheing pain without presence of syphilis , throbbing frontal headache never extend to occipute without presence of tubercular bridge , syphilis never agg in morning, vomiting with bilious fluid it presence bilious temprament with latent psora

Chandran Nambiar K C ‎:

@Avtar Singh Mavi: Sorry Sir, either you did not understand MODERN GENETICS, or you failed to comprehend what Hahnemann exactly said in the quoted aphorisms of ORGANON. Or, may be your are willfully misinterpreting genetics and organon due to some motives unknown to me.

DrPravin Dhole:

miasmatic analyisis never be a so called, it is scientific method ,

Chandran Nambiar K C ‎:

@DrPravin Dhole : Sir do not all these factors include in our concept of “totality of symptoms”?

Chandran Nambiar K C:

‎@DrPravin Dhole: Sir, do you think ‘misms’ are outside the purview of ‘totality of symptoms’. In my opinion, a similimum selected on the basis of ‘similarity of symtoms’ would cover everything including ‘miasms’

Chandran Nambiar K C ‎:

@DrPravin Dhole: Sir, I am not questioning the validity of “miasmatic analyisis”. I was trying to understand myself how this “miasmatic analyisis” could be related with ‘similia similibus curentur’. If you arrive at a prescription through ‘miasmatic analysis’, what will happen if that drug is not a similimum according to ‘similarity of symptoms’

DrPravin Dhole:

smymptoms similarity mean what? simply we cant match symp of patient to symp of drug only , individulization , totality of symp, chronic diseases classification , principle of chronic diseases, evaluation of miasm, confirmation of diathesis… , confirmation of constitution with symp, confirmation diathesis , confirmation of tempament , confirmation of inheritable tendencies and many other factor includes in symp similarities

 DrPravin Dhole:

how we will conclues these factors in case and where?

Chandran Nambiar K C ‎:

@DrPravin Dhole : I AGREE, SIR. All factors are included in ‘similarity of symptoms’. And only that is homeopathy.

Chandran Nambiar K C:

SIMILARITY OF SYMPTOMS means matching the ‘symptomatology’ of the drug with the ‘subjective and objective symptoms’ expressed by the patient. NOTHING LESS, NOTHING MORE.

Avtar Singh Mavi:

Before reading this I’ll just ask u for one thing..Be away from all prejudices…..In aphorism 5, Dr Hahnemann asks of the physician to take into consideration the physical constitution, his moral and intellectual char…acter, his habits and more which represents the Genetic Coding of the patient, this is all what the patient was born with. IN the Aphorism 81, Dr. Hahnemann has referred to an extremely ancient infecting agent which has passed hundreds of generations in millions of human beings ad is the cause of innumerable morbid diseases— have u ever thought of what Dr Hahnemann was referring to through this. It was Gene doctor because gene is the only thing which has passed through hundreds of generation in millions of human being and CAUSE of innumerable diseases as now the genetic scientists are saying all over world. DR. Hahnemann himself was a great scientist and nothing of his saying is away from science……..I think now it will be helpful for u to understand Dr. Hahnemann because even the newly admitted homoeopathic students of 1st year are understanding these things…. If u dont understand even now then u might b having some personal motives!!

Chandran Nambiar K C:

‎@Avtar Singh Mavi : “In aphorism 5, Dr Hahnemann asks of the physician to take into consideration the physical constitution, his moral and intellectual character, his habits and more”. Hahnemann said nothing about “genetic coding”. He new …nothing about ‘genetic coding’ at that time. It is we, who try to interpret “physical constitution, his moral and intellectual character, his habits and more” in terms of genetics and genetic coding. We should not put our words and interpretations into hahnemann’s mouth, hoping to prove that he new ‘every science’. That is impossible, sir.

Chandran Nambiar K C:

‎@Avtar Singh Mavi : “IN the Aphorism 81, Dr. Hahnemann has referred to an extremely ancient infecting agent which has passed hundreds of generations in millions of human beings ad is the cause of innumerable morbid diseases”. It is OUR IN…TERPRETATION that Dr Hahnemann was referring to GENES through this. He cannot “refer” about genes, since it was impossible for him to know anything about ‘genes’ at that time. He was referring to what he actually knew. We now interpret it on the basis of modern genetics.

Chandran Nambiar K C:

‎@Avtar Singh Mavi : Sir, the term “infecting agent” used by hahnemann by itself shows he has no any idea about “genes”. No body with minimum understanding of genetics would consider native “genes” of an organism as “infectious agents” for itself. The term “infectious agent” means some thing that “infects” the organism from external environment. That cannot be part of “genetic substance” of an organism.

Chandran Nambiar K C:

The term “infectious agent” Hahnemann used to describe “psora” and other “miasms” clearly shows that he did not consider “miasms” as part of genetic substance, and as such, it cannot be inherited through genes. By saying “inherited through …generations” hahneman only meant that these ‘miasms’ or ‘infectious agents’ were transferred from generation to generation as “infections”, not as “genes”. HIV infection can be transeferred from mother to infant, but it is not a ‘genetic inheritance’. It is only “infection”. That way, hahnemann only meant that the “infectious agents” of “psora” and other “venereal” miasms were transferred through generations of humanity. That has nothing to do with genetics. “INFECTIOUS AGENTS” cannot be inherited through GENES.

 Avtar Singh Mavi:

Doctor now I think that u need to read Genetics, once again….HIV virus is not being transferred from hundreds of generations in millions of human being nor any pathogen can be transferred which is only cause of every disease……..and what is psora sycosis and syphilis in ‘scientific’ language and how it is transferred in generations…. pls explain

Chandran Nambiar K C:

‎@Avtar Singh Mavi : SURE SIR. I HAVE TO READ AND UPDATE EVERYTHING REGULARLY

Avtar Singh Mavi:

Doctor if somebody calls u with the name Shekhar are ur characters going to change or will u be not the same person by only changing the name…….what if Dr. Hahnemann has not given the NAME Gene to that thing, cant it be gene which he has observed

Avtar Singh Mavi:

Lastly the thing is Doctor that we can wake a person who is sleeping but we cant wake a person who is pretending to sleep

Chandran Nambiar K C:

‎@Avtar Singh Mavi : Sir, Let us leave HIV as it is a new comer. LEPROSY was “transferred through generations” ranging for centuries as ‘infectious agents’. But nobody would dare to say that it was inherited through GENES. Same way, Hahnema…nn only meant that ITCH causing “infectious agents” were transferred through “hundreds of generations in millions of human beings”. TUBERCULOSIS is existing here through generations, transferred in the form of “infectious agents”. Only because hahnemann said that “infectious agents” or “miasms” were transferred through “hundreds of generations in millions of human beings”, why should we reach the conclusion that he was talking about GENES and GENETICS”? He was only talking about transferring of “infectious agents” or “miasms” through generations.

Chandran Nambiar K C:

‎@Avtar Singh Mavi : Sir, you have asked: “what is psora sycosis and syphilis in ‘scientific’ language and how it is transferred in generations…. pls explain”. SHALL I TRY TO EXPLAIN MY CONCEPTS ON THIS SUBJECT?

Chandran Nambiar K C:

‎@Avtar Singh Mavi : Sir, I have already explained my concepts regarding miasms in this doc. Would you please go to it: https://www.facebook.com/home.php?sk=group_126911884035337&ap=1#!/home.php?sk=group_126911884035337&view=doc&id=163731713686687

DrPravin Dhole:

OUR fundamental of low , is to satisfy the level of suceptibility, infection or specific bacteria or any virus is not inheritable , but suceptibility to the specific agent is an inheritable, constitutional miasmatic suceptibilies are inheritable , which desing the classification of diseases

Chandran Nambiar K C:

DrPravin Dhole : But sir, in aphorism 81 hahnemann says about “miasms’ as “infectious agents”. Let me quote: “the fact that this extremely ancient infecting agent has gradually passed, in some hundreds of generations, through many millions …of human organisms and has thus attained an incredible development, renders it in some measure conceivable how it can now display such innumerable morbid forms in the great family of mankind”. Is there any clue to show that he was talking about “constitutional miasmatic suceptibilies”? He was talking about “infectious agents”.. He was obviously not talking about “genetic inheritance”, but “transferring of infectious agents through generations”.

Chandran Nambiar K C:

ONLY THING IS THAT WE MISUNDERSTOOD “TRANSFER THROUGH GENERATIONS” AS “GENETIC INHERITANCE”.

Sayan Bhattacharya:

Dear doctors…i hav one question…

Have u seen any old skin disease reappear, during ur treatment of any chronic disease, like bronchial asthma, osteoarthritis??

If ur answer is yes…then U should not have any doubt about the efficacy of miasmatic theory.

Chandran Nambiar K C:

‎@Sayan Bhattacharya : Sir, it is not a question of “doubt about the efficacy of miasmatic theory”. We are trying to understand homeopathy better.

Chandran Nambiar K C:

‎@Sayan Bhattacharya : As for me, I have no any doubt regarding the existence of miasms, and the role it plays in chronic diseases. But regarding questions such as what is miasms, how it is inherited and such other details, I have difference of opinions with ‘classical’homeopaths. My perspective is different to homeopathy as a whole.

Chandran Nambiar K C:

In my view, ‘miasms’ are deformed protein molecules such as antibodies, and prions, which are native proteins subjected to ‘molecular imprinting’ by infectious agents. These deformed proteins can create ‘off-target’ molecular bindings and cause diverse types of chronic diseases.

Chandran Nambiar K C:

Antibodies formed against various types of ‘itch-causing’ and ‘inflamming’ infections are ‘psora’. Antibodies against various ‘cell-proliferating’ infections such as HPV and Gonorrhoea are ‘sycosis’. Antibodies against various ‘cell-degenerative’ infections such as ‘syphilis’ belong to ‘syphilitic’ miasm.

Chandran Nambiar K C:

These antibodies and prion-like defective proteins can remain in the organism life long, and can be transferred to offsprings through maternal blood

Chandran Nambiar K C:

WOULD SAY, ‘MOLECULAR IMPRINTED’ OR ‘DEFORMED’ PROTEIN MOLECULES SUCH AS ANTIBODIES AND PRION-LIKE PARTICLES ARE THE ‘MOLECULAR CARRIERS’ OF “MIASMS”.

Chandran Nambiar K C:

For example, antibodies formed against streptococcus skin infections and sorethroats are known to attack kidneys, joints and endocardial membranes, resulting in various chronic diseases. This can be included in ‘miasm’ of psora’.

Chandran Nambiar K C:

Antibodies formed against wart-forming’ human papilloma virus may bind to enzymes involved in gene expressions, thereby causing cellular proliferations, indurations and cancers. This can be included in ‘miasm’ of ‘sycosis’.

Chandran Nambiar K C:

Antibodies formed against ‘syphilis’ and similar infections attack different enzyme systems, resulting in cellular degenerations, gangrenes proteiolysis, tand such other conditions. These antibodies may be included in ‘syphilitic’ miasm.

DrPravin Dhole:

streptococcus , staphylococcus and sore throat are only cultivated in the tubercular or scrofulous spectrum, this suceptibility may tranfer to other system but the miasm will be latent sycotic

Amol Ravande:

to Chandran Nambiar K C sir, plz tell me one thing…we can consider that maternal antibodies are transfered to the child…but what about father? how his antibodies can get transferred to child?..

Amol Ravande::

do u mean to say that child will not get any miasmatic background from father? (as per your theory of antibodies)

Chandran Nambiar K C ‎:

@Amol Ravande: Sir, I don’t think antibodies or ‘miasms’ could be transferred from father to his child. Only genetically transferred traits can be inherited from father.

Chandran Nambiar K C:

‎@Amol Ravande: But see, if father has got an infection, that infection can be transferred to mother through intercourse or other means, and antibodies formed in her body. We are aware that women develop antibodies even against the semen of their sexual partners.

Chandran Nambiar K C ‎:

@Amol Ravande: Sir, I am not arguing to establish any thing. I AM ONLY THINKING ALOUD, AND SHARING MY THOUGHTS WITH YOU.

Chandran Nambiar K C:

I am only trying for a scientifically viable explanation for our concept of ‘miasm’

Chandran Nambiar K C:

I want to prove ‘theory of miasms’ scientifically; not to disprove it.

Amol Ravande:

sir….definately mother will develop antibodies if father has active disease…but if the disease, suppose gonorrhoea, is treated in father long back before marriage…and as per your concept of miasm as disease,.. now the father has sycosis miasm…and now mother conceivs…do u mean to say that child will not born with sycotic predominance?

Chandran Nambiar K C:

‎@Amol Ravande : As per my existing knowledge, I see no chance for that.

Chandran Nambiar K C:

I have not learned bout a molecular mechanism to transfer information regarding different antibodies into genetic codes

Chandran Nambiar K C:

I do not know whether there exist a mechanism of ‘reverse transcription’ of proteins into RNA and then into DNA. If such a mechanism actually exist, it may be possible.

Amol Ravande:

sir…i’m much junior to u…but i must say that i’m not with u regarding this concept…

Chandran Nambiar K C:

‎@Amol Ravande : Sir, I am not worried whether people support me or not. I am saying my convictions and original thoughts. At this stage of evolution, I should not expect people to agree with me, because I am talking to a community trained in classical homeopathy, and many of my concepts go against what you are taught.

Amol Ravande:

ya ofcourse sir….but these comments will help u to improve ur concept…to find lacunae in ur concept..i think we should keep our minds open…that’s why i was trying to explain all these things to u…i have no intensions to hurt or criticise u

Partha Sarathi Ray

I’m re-posting:

@Nambiar Sir: Your answer “As per my existing knowledge, I see no chance for that.” regarding the question of Dr.Ravande sounded much surprising to me.If the new born is not inheriting Sycosis (in this example),then how does he show all latent and prominent symptoms of sycosis after birth and at latter stage?And how can our antisycotic drugs cure him?

Chandran Nambiar K C

If ‘miasms’ are molecular imprinted proteins such as antibodies and prion-like particles, it is obvious that antibodies cannot be inherited from father to his child. But it can be transferred to child through maternal blood.

Chandran Nambiar K C

Regarding ‘cure by anti-sycotic drugs’- No drug can cure if it is not ‘similimum’. A similimum will cure if it is antisycotic or not.

Amol Ravande

so u mean cure has nothing to do with miasm? then why hahnemann has given theory of miasms?

Chandran Nambiar K C

‎@Amol Ravande : “miasms’ play a role in curing ‘miasmatic diseases. But there are a lot of non-miasmatic diseases. I am questioning the idea that all chronic diseases are miasmatic. I have many times pointed out that hahnemann classified chronic diseases into ‘miasmatic’ and ‘non miasmatic’

Chandran Nambiar K C

‎@Amol Ravande : Sir, while saying “hahnemann has given theory of miasms”, you should not forget that he also said about “non-miasmatic’ diseases.

Chandran Nambiar K C  

Please listen: In Organon : Aphorism 204(Sixth Edition) Hahnemann says:

“If we deduct all chronic affections, ailments and diseases that depend on a persistent unhealthy mode of living, as also those innumerable medicinal maladies caused by …the irrational,… persistent, harassing and pernicious treatment of diseases often only of trivial character by physicians of the old school, most the remainder of chronic diseases result from the development of these three chronic miasms, internal syphilis, internal sycosis, but chiefly and in infinitely greater proportion, internal psora”

This statement shows, Hahneman considered a class of ‘chronic’ diseases’ originating from ‘persistent unhealthy mode of living’ and ‘innumerable medicinal maladies’, other than ‘miasmatic chronic diseases’.

Chandran Nambiar K C

That means, when treating ‘chronic diseases’ originating from ‘persistent unhealthy mode of living’ and ‘innumerable medicinal maladies’, we need not worry about psora, syphilis or sycosis, but we can treat according to ‘similia similibu cu……rentur’. Remember, most of the ‘chronic diseases’ originating from occupational, environmental, nutritional, drug-induced, infectious and such others belong to the class of “chronic diseases originating from ‘persistent unhealthy mode of living’ and ‘innumerable medicinal maladies”. THEY ARE NOT CAUSED BY MIASMS OF PSORA, SYPHILIS OR SYCOSIS.

Chandran Nambiar K C

It is obvious that Hahnemann excluded “all chronic affections, ailments and diseases that depend on a persistent unhealthy mode of living, as also those innumerable medicinal maladies” while talking about “chronic diseases” of “miasmatic origin”.

Chandran Nambiar K C

When treating chronic diseases, first we have to examine whether they belong this group of “chronic affections, ailments and diseases that depend on a persistent unhealthy mode of living, as also those innumerable medicinal maladies” . If so we need not consider miasms, but to find a similimum on the basis of ‘similia similibus curentur’.

Chandran Nambiar K C

Hahnemann even sub-divided “non-miasmatic chronic diseases” into two: a) All chronic affections, ailments and diseases that depend on a ‘persistent unhealthy mode of living’. b) those ‘innumerable medicinal maladies’. Why the ‘followers of …the master so far ignored this? When selecting a drug on the basis of ‘miasmatic analysis’, can we ignore ‘similia similibus curentur’? If you prescribe a drug without considering ‘similarity’ of symptoms, how can we claim that it is homeopathy? Did Hahnemann ever advise to replace the therapeutic principle of ‘similia similibus curentur’ with ‘theory of miasms’?

Amol Ravande

i must mention that during hahnemann’s time allopathic treatment was very harsh…leeching, bloodletting, use of mercurial compounds was very much regularly performed. this led to severe suppression and he termed it as medicinal disease…….now the fact is how many of such cases we see now a days? what we see regularly is the diseases like DM, TUMORS, HTN, for which we have to treat the patient with antimiasmatic remedy….there is no point in just making theoratical debates…we have to think about pratical applicability…

Amol Ravande

from your perspective…plz tell me which are nonmiasmatic diseases?

Chandran Nambiar K C

‎@Partha Sarathi Ray: Sir, your question “if the new born is not inheriting Sycosis (in this example),then how does he show all latent and prominent symptoms of sycosis after birth and at latter stage? And how can our antisycotic drugs cure… him?” is very important.

You also said that my answer regarding the question of genetic transfer of sycosis from father to child “as per my existing knowledge, I see no chance for that.” sounded much surprising to you.

First of all please note that Hahnemann described “miasms” as an “infectious agent”, which was “inherited through generations of of humanity”. Only because he said about ‘inheriting through generations’, why should we jump to the conclusion that hahnemann was talking about ‘genetic transfer of miasms’? Remember, nothing was known about modern genetics during his time, and he was not in a position to think about ‘genetic transfer’. “Inherited through generations’ only means that the “infectious agents” were transferred through generations. That means, the infections remained here all along many generations. The term ‘inheritance’ is used not only for ‘genetic inheritance’. We use that term for ‘inheritance of property rights’, ‘inheritance of titles’ and many other things. Hahnemann only could have meant that type of ‘inheritance of infectious agents’.

 

In our anxiety to make the “master” the “greatest scientist’ and ‘geneticist’ ever lived, we are putting our interpretations and words into his mouth. That is very inappropriate.

Coming to the point of inheritance of ‘sycosis’ from father to child. I have earlier explained that what hahnemann called “sycotic miasm’ was actually a ‘mixed miasm’ arising from sexually transmitted gonorrhoea, human papilloma virus and various yeast infections, that can cause infections in genital tract, warts, uterine fibroids and various other chronic ailments. According to me, the miasm of ‘sycosis’ is the antibodies generated against these infections, which can cause diverse types of chronic diseases including tumors and cancers through off-target molecular bindings.

If a man is infected in his genital tract with these mixed infections, after expressing a few initial symptoms, the infection turns silent, and he would appear to be normal and free of disease. But he can transfer his infections to his sexual partner life long. In women also, after a few initial symptoms such as UTI and vaginal discharges, infections turns silent. But she can infect anybody who engages in sexual intercourse with her. If the man was already infected earlier, both of them would not show any symptoms of infection. The woman can transfer the ‘infectious agents’ to her child from genital tract during delivery, or transfer the antibodies to the infant through maternal blood. Any way, ‘infectious agents’ of ‘sycotic miasms’ would be transferred to the next generation. There is no any involvement of GENETIC TRANSFER here. If the father is infected, there is all chance for ‘transfer of miasm’ to the infant through the mediation of mother.

If still you want to ‘believe’ or ‘establish’ that ‘sycosis is inherited through GENES, I am helpless, sir.

Amol Ravande

sir…i must mention that after taking treatment..either allopathic or homoeopathic, even a trace of bacteria didnot remain in semen of father…do u mean to say that once someone gets gonorrhoea..lifelong bacterias are present in his semen?

Chandran Nambiar K C

‎@Amol Ravande: It is not a question of ‘my perspective’. Hahnemann has already told about the ‘non-miasmatic’ chronic diseases. I have quoted him many times during this conversation.

In Organon : Aphorism 204(Sixth Edition) Hahnemann says:…

“If we deduct all chronic affections, ailments and diseases that depend on a persistent unhealthy mode of living, as also those innumerable medicinal maladies caused by the irrational,… persistent, harassing and pernicious treatment of diseases often only of trivial character by physicians of the old school, most the remainder of chronic diseases result from the development of these three chronic miasms, internal syphilis, internal sycosis, but chiefly and in infinitely greater proportion, internal psora”

This statement shows, Hahneman considered a class of ‘chronic’ diseases’ originating from ‘persistent unhealthy mode of living’ and ‘innumerable medicinal maladies’, other than ‘miasmatic chronic diseases’.

It is obvious that Hahnemann excluded “all chronic affections, ailments and diseases that depend on a persistent unhealthy mode of living, as also those innumerable medicinal maladies” while talking about “chronic diseases” of “miasmatic origin”.

We should notice that hahnemann was well conscious about two distinct classes of chronic diseases: 1. All chronic affections, ailments and diseases that depend on a ‘persistent unhealthy mode of living’, as also those ‘innumerable medicinal maladies’. 2. Miasmatic chronic diseases arising from psora, syphilis and sycosis. He never said one class is ‘pseudo’ and other is ‘true’.

Hahnemann even sub-divided “non-miasmatic chronic diseases” into two: a) All chronic affections, ailments and diseases that depend on a ‘persistent unhealthy mode of living’. b) those ‘innumerable medicinal maladies’. Why the ‘followers of the master so far ignored this?

When treating chronic diseases, first we have to examine whether they belong this group of “chronic affections, ailments and diseases that depend on a persistent unhealthy mode of living, as also those innumerable medicinal maladies” . If so we need not consider miasms, but to find a similimum on the basis of ‘similia similibus curentur’.

Chandran Nambiar K C

Amol Ravande: Sir, I am not available for an argument on this topic. I have explained my convictions here. If you feel I am wrong, and if you want to believe otherwise, let it be so. I have decided not to engage in arguments. I would explai…n my ideas. That is all. All of us are prejudiced, and engage in discussions only to disprove and defeat others. I have decided to avoid such arguments. If anybody believe I am wrong, I will not try to convince him through arguments.

Chandran Nambiar K C ‎

@Amol Ravande : Sir, please comment on what I said about ‘non-miasmatic diseases’. LET US DISCUSS

Chandran Nambiar K C

For the time being, let us concentrate on two points:. i. Non-miasmatic diseases. 2.whether miasms are genetically inherited.

Chandran Nambiar K C

‎@Amol Ravande : From hahnemanns descriptions of sycosis, I do not see ‘sycosis’ as a simple gonorrhoeal miasm. Gonnrorrhoea cannot cause warts or uterine fibroids. It might me a mixed infection of gonorroea, HPV and yeast infections, all sexually transmitted.

Chandran Nambiar K C

The problem is, we have been trained all these years in such a way that we cannot think about chronic diseases without linking with syphilis, sycosis and psora. We totally ignored hahnemanns observations regarding ‘non-miasmatic chronic di…seases’. You are not willing to hear somebody saying differently from what you have been taught. If we observe the various chronic diseass we encounter daily, we would see that most of them belong to “chronic affections, ailments and diseases that depend on a persistent unhealthy mode of living, as also those innumerable medicinal maladies”, which are ‘non-miasmatic’ according to hahnemann.. Those life style diseases, effects of vaccinations, drugging, environmental toxicit, occupational diseases. nutritional diseases, all belong to this class of ‘non-miasmatic’ diseases.

Chandran Nambiar K C

I know, it will be difficult for you to agree with what I say, because you have been trained to think in a different way. I WOULD REQUEST YOU TO APPLY SOME LOGIC AND RATIONAL THINKING.

Chandran Nambiar K C :

One of the most confusing and most controversial part of homeopathy is the theory of ‘miasms’ and ‘chronic diseases’. Each homeopath understands, interprets and applies this theory in his own way. I think we need a logical and universally acceptable understanding of this concept, that would fit to the available scientific knowledge system and clinical experiences of homeopaths, and provide guidance in our practice.

  Chandran Nambiar K C :

One respected homeopath responded to this statement: “dont worry even based on the old theory it is working wonderfully”. That shows he is not much pleased about my attempts of explaining ‘miasm’ and homeopathy at large. I know there would …be many people to agree with him. They are not ‘worried’ because they think homeopathy ‘works well even based on old theories’. I would like to tell them, any objective law of nature would work ‘wonderfully’ even if we do not know ‘how it works’ or even if we interpreted it wrongly. Electricity was ‘working’ here much before we knew anything about electricity. But knowing ‘how exactly it works’ would help us to utilize it more effectively. I think it is applicable to our scientific understanding of ‘miasms’ also. “As far as something is working well, we need not try to understand it better” is a way of thinking not acceptable to scientific-minded people. If that philosophy is accepted, there would not be any scientific research, since everything around us “working well” even without we knowing “how exactly it works”!

Chandran Nambiar K C :

In Para 12 of CHRONIC DISEASES, Hahnemann says: “PSORA has thus become the most infectious and most general of all the chronic miasmas”. That means hahnemann talks about a ‘psora’ that can be got transferred from person to to person as INFE…CTIONS. Do we have to believe that we will get infected with ‘PSORIC MIASM’ by some sort of physical contact with a ‘PSORIC’ person?

If PSORA is “immaterial” and “dynamic”, and if it is MOST INFECTIOUS as hahnemann says, would it be transferred from a PSORIC man to a NON-PSORIC man in a “dynamic” way, without the mediation of any “INFECTIOUS MATERIALS? I have no idea about the mean distance between persons required for such a “dynamic infection” of psora to happen. Some people say that “dynamic drug powers” can be transferred to distant places. Can PSORA also can infect “dynamically” from person to person who are at very distant places?

Chandran Nambiar K C:

Homeopathic understanding and management of ‘chronic disease’ is based on the concept of ‘miasms’. Hahnemann has provided detailed explanations regarding three types of ‘miasms’ such as ‘psora’, ‘syphills’ and ‘sycosis’. Theory of ‘miasms’… and chronic diseases were developed during later part of Hahnemann’s life, when he learned from his clinical experience that medicines selected on the basis of similarity of symptoms as he advocated earlier offered only temporary relief to the most patients.

According to his theory of ‘chronic diseases’, ‘psora’, the ‘miasm’ of suppressed ‘itch’, is the underlying primary cause of all chronic diseases other than those of ‘venereal’ origin. ‘Psora’ is said to be the greatest obstruction to cure. Other two miasms, ‘syphilis’ and ‘sycosis’ are considered to be miasms of venereal diseases, ‘syphilis’ and ‘gonorrhoea’ respectively. Hahnemann considered ‘psora’ to be the most important and universal ‘miasm’. According to his theory, unless this ‘miasm’ or ‘disease poison’ is eradicated with appropriate ‘anti-psoric’ drugs, permanent and lasting cure cannot be attained.

The primary forms of expression of ‘psora’ is considered to be the itching eruptions on skin, that of ‘syphilis’ un-healing tissue destructions like malignant ulcers, and that of ‘sycosis’ warts and condylomata.

Chandran Nambiar K C:

Now, let us try to analyze the concept of miasms and chronic diseases in the light of scientific understanding of molecular biology, ‘similia similibus curentur’ and ‘potentization’.

Human organism is constantly exposed to the attacks of various types of exogenous and endogenous foreign molecules and ions. They may bind to the complex native biological molecules, thereby deforming their configuration and making them incapable of participating in the normal bio-chemical interactions. As per scientific view, this phenomenon underlies the molecular basis of most pathological conditions.

If the pathological foreign molecules are of protein nature, native biological defense proteins having configurational affinity to these foreign proteins attaches to them, destroys and removes them from the organism as part of body’s defense mechanism. During this defense process, some of the involved native protein molecules get configurationally deformed by the interaction with foreign molecules. Native protein molecules so deformed will be carrying the 3-D spacial impressions of the interacted foreign molecules on their periphery. These impressions exist as three dimensional pockets, having a configuration complementary to that of foreign proteins. These molecular imprinted proteins thus become incapacitated for their normal biological processes, and remain a burden in the organism. Antibodies actually belong to this class of such deformed globulin proteins, subjected to ‘molecular imprinting’ by foreign proteins.

Certain endogenous molecules and ions such as hormones, neuro-chemicals, and other metabolic byproducts such as super-oxides, when circulated in excess, may also attach to various bio-molecules other than their natural targets, and induce configurational changes in them.

These deformed native proteins may circulate in the system, and accidentally attach to various bio-molecules having complementary configurational affinity, thereby creating various molecular errors and pathological deviations.

Configurational changes happening in enzymes of protein nature involved with genetic expressions and DNA synthesis may ultimately lead to various types of proteinopathies, or may result in mutations happening in genetic substance itself, with subsequent hereditary diseases. If the enzymes involved in genetic expressions get deformed by molecular imprinting, it may affect the process of normal protein synthesis, and produce related pathological conditions. It may be noted that heavy metal ions and certain poisonous substances such as alkaloids and organophos chemicals also can inhibit the enzymes associated with DNA synthesis, and create genetic errors.

Chandran Nambiar K C:

Obviously, modern scientific knowledge regarding subjects such as antibodies, proteinopathies, genetic expressions, molecular imprinted proteins, etc., were not available during the era of Hahnemann, when he undertook the study of chronic d…iseases. Had he understood the exact bio–molecular basis of these phenomena, he would have provided a theory of chronic diseases entirely different from that he had formulated. At that time, it was the wonderful insight of the great genius of Hahnemann that enabled him to observe the deep-seated factors playing behind the chronic diseases that he called ‘miasms’. During that period, even before the appearance of antibiotics modern microscope, most dreaded diseases such as eczema, leprosy, syphilis and gonorrhoea were rampant in europe. He observed that in spite of the various crude forms of treatments available then, these diseases continued their manifestations during the whole life span of patients. Naturally, his theory of chronic disease was more involved with the long term effects of these diseases. He used the term ‘miasm’ to describe these chronic disease factors. By the term ‘miasm’, he really meant ‘disease poisons’. The miasm of ‘itch’(and leprosy) was called as ‘psora’, the ‘miasm of syphilis as ‘syphilis’, and that of gonorrhoea as ‘sycosis’. Now, based on modern scientific knowledge, we can say that ‘miasms’ are the antibodies or ‘molecular imprinted proteins’ created in the organism due to the interaction of native proteins with various bacterial, viral or fungal toxins of protein nature. Various environmental allergens, and certain endogenous molecules and metabolic bye-products may also imprint up on native defense proteins and convert them into chronic ‘miasms’.

Chandran Nambiar K C:

Antibodies produced in the organism against scabies (itch), leprosy, and tuberculosis belong to same class, and give positive reaction to ‘tuberculin’ antigen tests. This indicates that toxins released by these bacteria have certain similar… molecular groups in them, and the molecular imprints or antibodies against those groups also have certain configurational similarities. Actually, these ‘molecular imprints’ belong to the ‘miasms’ of ‘psora’ described by Hahnemann. Homeopaths already know that potentized ‘tuberculinum’, ‘bacillinum’, and ‘psorinum’ play a wonderful role in the treatment of scabies and other skin eruptions, and the chronic conditions related with them.

Chandran Nambiar K C:

It may be interesting to observe that toxins released by bacteria belonging to mycobacterium group, are molecules containing ‘sulphur’ in their active groups. The presence of sulphur-containing amino acid called cysteine is responsible for …this factor. During infection, bacterial toxins bind to the biological molecules of organism using this sulphide group. Naturally, ‘molecular imprints’ or antibodies of these bacterial toxins will have complementary negative configurations of this ‘sulphide’ groups. These ‘molecular imprints’ can attack various bio-molecules in diverse bio-chemic pathways, resulting in different types of constitutional diseases of ‘psoric’ nature. We already know that the antibodies produced against bacterial skin infections may attack heart, kidney, brain, and other vital organs causing different types of diseases. Streptococcal and staphylococcal antibodies formed against acute throat and teeth infections may attack synovial membranes of joints, endocardial linings, and valvular structures of heart. During drug proving, sulphur also binds to the same molecular targets as the sulphur-containing bacterial toxins. The similarity between certain symptom groups expressed by these bacterial infections and the homeopathic provings of sulphur may be specifically noted. Here we get the scientific explanation for the observation of Hahnemann that potentized sulphur is the most important ‘antipsoric’ medicine, or ‘The King of Antipsorics’. It is already known that the amino acid called ‘cysteine’, which contains ‘sulphide’ groups, play an important role in almost all molecular interactions in the organism, involving protein molecules. It may be the reason for the appearance of so many symptom groups, involving almost every organ of the body, in the homoeopathic proving of sulphur. Potentized sulphur can compete with the molecular imprints or antibodies, in their interactions with biological molecules, and act as a most powerful ‘anti psoric’ drug.

Equipped with the knowledge accumulated by modern science in recent years, we are now in a position to provide satisfactory answer to the centuries old riddle of ‘miasm’ and ‘chronic diseases’. There is no further scope or space for metaphysical speculations any more.

Chandran Nambiar K C:

In recent years, we have heard a lot about researches on a certain class of disease causing agents, called ‘prions’. Prions are deformed complex protein molecules acting as pathogens. Prions were invented during the research on ‘scrapie’ or… ‘mad cow disease’. The actual mechanism of normal protein molecules turning into ‘prions’ has not been well understood yet. Recent studies on the molecular basis of Alzhiemer’s disease, also indicates to the role of deformed proteins in its pathology. Molecular changes associated with normal aging process also have to be examined from this stand point. In my opinion, these issues can be solved from the viewpoint of ‘molecular imprinting in proteins’. More studies are required in this direction.

Chandran Nambiar K C:

This is an era of vaccinations. Every human being is subjected to a series of vaccination protocols from the moment of birth, to protect from various diseases. We have to worry about the unknown long term after effects of these vaccinations…. Live or attenuated viruses are introduced into the organism to produce antibodies against pathological infections. Actually, this process induces ‘molecular imprinting’ of native proteins, with the foreign proteins contained in the vaccines. Obviously, the molecular imprints or antibodies thus formed, shall act as ‘miasms’ in the organism. If this type of molecular deformity happens in proteins associated with DNA synthesis or genetic expression, it may result in serious genetic abnormalities. It is high time that we realized this dangerous possibility associated with vaccinations. All these deformed proteins created by vaccinations, act as ‘miasms’, and throw humanity into a sea of complicated chronic diseases much beyond the level observed even by Hahnemann.

Chandran Nambiar K C:

For example, let us consider PSORA. It is the antibodies formed against ITCH caused by SCABIE MITES. These SCABIES MITES carries mycobacteria on them, and that is why TUBERCULIN TEST is positive for scabies, tuberculosis and leprosy patient…s. Their antibodies are similar. ALL COMES UNDER PSORA

ANTIBODIES ARE TRANSFERRED FROM MOTHERS TO OFFSPRING THROUGH MATERNAL BLOOD

DEFORMED PROTEINS CAN BIND TO REGULATORY ENZYMES INVOLVED IN DNA SYNTHESIS AND GENE EXPRESSIONS, AND THAT WAY AFFECT THE GENETIC SUBSTANCE ALSO.

Chandran Nambiar K C:

It is interesting to note that even though hahnemann described PSORA as a miasm caused by ‘itch infections’, he did not limit this ‘itch’ to scabies alone. He included leprosy, fungal infections and various other other similar ‘itch’ produc…ing skin infections as the causative factors of psora. It is obvious that he was talking about a ‘class of infections’ as causative agents of PSORA. We know that all these infections produce ‘antibodies’ in the organism by a process of ‘molecular imprinting of native proteins’ with the infectious toxins. Although the natural targets of these antibodies are the infectious agents themselves, antibodies move in the organism freely and may bind to different ‘off-target molecules having configurations similar to natural targets. Such off-target actions of these ‘antibodies’(molecular imprinted proteins or malformed proteins) may cause diverse types of ‘molecular errors’ in various biochemical pathways, resulting in different chronic diseases that we consider belonging to PSORA. According to my view ‘miasm of psora’ includes all antibodies that can trigger a series of molecular interactions that would prompt the ‘regulatory proteins of gene expressions’, to induce the genes to synthesize various ‘inflammatory’ molecules. That is why PSORA is considered to be a miasm behind INFLAMMATORY diseases. According to this interpretation, PSORA is not a single miasm, but a CLASS of miasm or a CLASS of antibodies that can induce genes to produce proteins that would cause inflammatory changes in the system. We can see, all diseases and their symptoms hahnemann included in PSORA exactly fit to this interpretation. LET US SUM UP: A CLASS OF ANTIBODIES AND MALFORMED PROTEINS ARISING FROM MOLECULAR IMPRINTING OF NATIVE PROTIENS WITH A CLASS OF INFECTIOUS TOXINS ARE THE “MOLECULAR CARRIERS OF PSORA”. THESE ANTIBODIES INDUCE THE GENETIC SUBSTANCE TO PRODUCE INFLAMMATORY MOLECULES, THEREBY RESULTING IN INFLAMMATORY CHANGES IN THE ORGANISM.

Chandran Nambiar K C:

In the same way as PSORA, we can see that SYCOSIS is a CLASS OF MIASM, consisting of antibodies created by by gonorrhoea, human papiloma virus, vaccinosis etc.These antibodies induce GENETIC SYSTEM to produce INDURATIONS , WARTY GROWTHS AND… TUMORS in the organism.

SYPHILITIC miasm consists of a class of antibodies and malformed proteins that induce GENETIC SYSTEM to produce molecules that may cause CELLULAR DESTRUCTION, NON-HEALING ULCERS, NECROSIS etc.

There may be thousands of miasms (antibodies and malformed proteins) in the organism. But all these diverse miasms could be broadly classified into PSORA(INFLAMMATORY), SYCOSIS(INDURATIONS), and SYPHILIS(CELLULAR DECAY). Thus we can say, there exists THREE CLASSES OF MIASMS

Harishkumar Shinde:

Dear sir, you are started a very good discussion on the subject of MIASM here but therotically understanding miasm is a different thing and clinically applying miasms in practic is very different thing. so the miasm states the present disea…se state and it shows the path of the prognosis of disease, and miasm gives clue for perfect prescription. after proper studying your blog i am ready to discuss on miasms we will discuss, Thanks

Yogesh Upadhyay Homoeopath:

very good explanation by chandran sir really gud to discuss this will elaborate our knowledge of miasm

Chandran Nambiar K C:

‎@Yogesh Upadhyay Homoeopath and @Harishkumar Shinde : Thank you sir. I expect a meaningful discourse between us on this topic.

Chandran Nambiar K C:

‎@Yogesh Upadhyay Homoeopath and @Harishkumar Shinde : I am waiting for your comments to take this thread forward.

Manish Kumar:

chandran sir as i read all the explanation regarding miasm is very perticular,you did not consider the individual reaction regarding the miasmatic state,the progress of disease itself defying the miasmatic state of individual.the thinking and behaviour of the individual also carry significance,when we categorize miasm,not only pathological condition responsible for miasmatic expression.

Chandran Nambiar K C:

‎@Manish Kumar: Sir, “the thinking and behavior of the individual” also has a molecular level process behind it. I think we need not consider mental and physical aspects as separate entities. When I talk about pathology I mean ‘molecular pathology’ which is common for mental and physical ‘expressions’.

Manish Kumar:

regarding molecular biology as you raised the question regarding heriditary mechanism of miasm,yes miasm can be travel through one generation to another,hapten is a molecule made up of polypeptide chain which responsible for it,and whwn we …talk about antibodies only iGg immunoglobulin can cross the placental barrier,this immunoglobulin help the palsma cell to form antibodies,and manufacture the interferon and inflamatory substance,miasmgives us clue to observe the bhaviour of the disease which reflect in individual,and it cons

Chandran Nambiar K C:

@ Manish Kumar: Sir, I feel we share a lot of common concepts regarding ‘miasms’.

Manish Kumar:

why not sir it’s my pleasure

Manish Kumar:

and it can travel from distence also,because if any remedy show it’s manifestation to individual from distence then why not it affect the over individuality of the patient and miasm is also an integral part of individual constitution so it can work

Chandran Nambiar K C:

‎@Manish Kumar ; Sir, kindly explain your statement “it can travel from distance”. I got confused on that point’

Sayan Bhattacharya:

@ Robert and J.H. Allen…has written quite beautifully much about miasms…but in reality very few teachers can teach us MIASMS. I mean at the bed side.

Aude Sapere:

Beautifly illustrated. Thank u Sir!

Kranti Kumar:

THANKS FOR GIVING AN IN VIEW REGARDING THE UNDERSTANDING OF MIASM IN TODAYS CONTEXT BUT I THINK A MIASM IS VERY MUCH AN INFECTIVE PATHOLOGICAL AGENCY WHICH ONCE INFECTS THE HEALHY ANIMAL ECONOMY CREATS SOME PERMANENT DISTURBANCE WHICH IS CAR…RIED FORWARD IN THE ONCOMING GENERATION IF NOT BEING TREATED BY LAW OF SIMILIA. PSORA IS THE FIRST AND THE FOREMOST MIASM WHICH HAS INFECTED ANIMAL BODY AND MADE IT MORE PRONE TO BE INFECTED BY THE OTHER TWO FUNDAMENTAL MIASMS CALLED SYPHILLIS AND SYCOSIS WHICH ARE THE VENERAL AND THE GONNORHHOEL POISONS RESPECTIVELY MOREOVER IT MAY ALSO BE POSSIBLE LIKE THE OTHER TWO MIASMS MIGHT BE HAVING INITIAL PRECURSOR SYMPTOMS SIMULATING PSORIC MANIFESTATIONS WHICH LATER MAY PROGRESS IN A FORM OF THERE RESPECTIVE INFECTIOUS AGENTS.

Manasbikash Mandal :

as per my knowledge,homoeopathy cannot be completed without miasm. it is the heart of homoeopathy.

Chandran Nambiar K C:

‎@Manasbikash Mandal : I agree sir. Understanding of ‘miasms’ working an individual is essential for a therapeutic intervention to offer ‘total cure’. But I was trying to explain what is exactly the ‘material basis’ of ‘miasms’.

Chandran Nambiar K C:

‎@Kranti Kumar: I agree with your statement “MIASM IS VERY MUCH AN INFECTIVE PATHOLOGICAL AGENCY WHICH ONCE INFECTS THE HEALHY ANIMAL ECONOMY CREATES SOME PERMANENT DISTURBANCE”. I was trying to explain this phenomenon in terms of antibodies and malformed proteins formed by molecular imprinting of native proteins by exogenous and endogenous pathogenic agents.

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