Without A Scientifically Viable ‘Working Hypothesis’, You Cannot Conduct A Genuine Research On ‘How Homeopathy Works’
WITHOUT A SCIENTIFICALLY VIABLE WORKING HYPOTHESIS AS A SPRINGBOARD OF FURTHER ACTIONS, YOU CANNOT CONDUCT A GENUINE SCIENTIFIC RESEARCH. OUR ‘NANO-PARTICLE RESEARCHERS’ OF HOMEOPATHY TRIED TO DO IT WITHOUT SUCH A HYPOTHESIS, WHICH INEVITABLY LED THEM TO POORLY CONCEIVED EXPERIMENTS, INACCURATE OBSERVATIONS, WRONG INTERPRETATIONS, FOOLISH CONCLUSIONS AND TOTALLY ABSURD THEORIES.
SCIENTIFIC METHOD is a body of techniques for investigating phenomena, acquiring new knowledge, or correcting and integrating previous knowledge. To be termed scientific, a method of inquiry must be based on empirical and measurable evidence subject to specific principles of reasoning. It is ‘a method or procedure consisting in systematic observation, measurement, and experiment, and the formulation, testing, and modification of a proposed HYPOTHESIS.
The chief characteristic which distinguishes a scientific method of inquiry from other methods of acquiring knowledge is that scientists seek to let reality speak for itself. Hypothesis is raised to the status of THEORY when the predictions based on hypothesis are confirmed. Hypothesis is discarded or modified when its predictions prove false.
Scientific researchers proposes a HYPOTHESIS as explanations for an unexplained but known phenomenon, and design experimental studies to test this hypothesis via PREDICTIONS which can be derived from them. These steps must be repeatable, to guard against mistake or confusion in any particular experimenter. Certain researches may encompass wider domains of inquiry that may bind many independently derived hypotheses together in a coherent, supportive structure.
A hypothesis is derived as a tentative answer to a naturally arising question regarding a known phenomenon. It is a conjecture based on the knowledge obtained while formulating the question.
To be considered scientifically viable, a hypothesis must be FALSIFIABLE, meaning that one can identify a possible outcome of an experiment that conflicts with predictions deduced from the hypothesis through a NULL HYPOTHESIS; otherwise, it cannot be meaningfully tested.
According to scientific method, PREDICTIONS, TESTING and ANALYSIS are the essential steps in the validation of a scientific hypothesis.
MIT proposes the following HYPOTHESIS as an answer to the question HOW HOMEOPATHY WORKS. We have to PROVE it or DISPROVE it.
“Homeopathy is a therapeutic method of curing diseases by using ‘molecular imprints’ of drug substances, which in ‘molecular forms’ could produce ‘symptoms’ similar to those presented by the patient. ‘Similarity’ of drug symptoms and disease symptoms indicate that the drug molecules and pathogenic molecules have ‘similar’ functional groups, by which they could bind to ‘similar’ biological molecules, produce ‘similar’ molecular inhibitions that caused ‘similar’ molecular pathology which are expressed through ‘similar’ subjective and objective ‘symptoms’. Molecular imprints of ‘similar’ drug molecules can act as artificial binding sites for ‘similar’ pathogenic molecules due to complementary configurational affinity, thereby deactivating them and relieving the biological molecules from pathological inhibitions, which amounts to ‘cure’. This the scientific meaning of Similia Similibus Curentur.”
Essential part of this HYPOTHESIS that has to be proved or disproved first is that homeopathic potentization is a process of MOLECULAR IMPRINTING, and the active principles of potentized drugs are MOLECULAR IMPRINTS of drug molecules. This has to be proved or disproved according to scientific methods, to make homeopathy a legitimate medical science.
PREDICTIONS formulated for proving MIT HYPOTHESIS are:
1. If ‘molecular imprinting’ concept is right, there will not any single ‘molecule’ of original drug substance remaining in potencies above avogadro limit, if they are genuinely potentized.
2. If ‘molecular imprinting’ concept is right, chemical analysis of high potency drugs and plain water-alcohol mixture will prove they have same chemical constitution.
3. If ‘molecular imprinting’ concept is right, potentized drugs have therapeutic effects if used as per indications, but plain water-alcohol mixture will not exhibit any therapeutic effect.
4. If ‘molecular imprinting’ concept is right, spectrometric studies will show that high potency drugs and plain water-alcohol mixtures are entirely different in their supra-molecular organizations.
5. If ‘molecular imprinting’ concept is right, in vitro and in vivo studies will prove that high potency drugs have biological properties that are reverse to those of their molecular forms (below 12c)
6. If ‘molecular imprinting’ concept is right, high potency drugs should be capable of antidoting or neutralizing the biological effects of molecular forms of same drugs.
THESE PREDICTIONS HAVE TO BE PROVED OR DISPROVED THROUGH SCIENTIFIC EXPERIMENTS.
- Posted in: Homeopathy Articles
- Tagged: biochemistry, homeopathy research
REDEFINING HOMEOPATHY 
1. Number of ‘molecules’ or ‘atoms’ in any given quantity of any substances will be limited by avogadro number, which is an accepted scientific fact. Otherwise, somebody will have to prove that either avogadro number is wrong, or, ‘new matter’ is continuously generated from nothingness by the process of potentization.
In ultra dilutions, where the substance is diluted millions of times above avogadro limit, where from you expect this unending supply of drug molecules you imagine to lay “tightly entrapped by solvent molecules”?
Even if some drug molecules remain in the whole volume of a solution, how could you imagine those “rare” molecules to be present in each and every drops or minute fractions of drops of potentized drugs used by homeopaths as ‘doses’? How could you imagine to explain the medicinal properties of each and every drops of ultradiluted drugs on the basis of these ‘drug molecules’ that may be only very rarely distributed in a large volume of diluted drug?
Sir, you said that “ordinary spectrophotometric data cannot reveal” the presence of drug moleciles lying “entrapped in solvent molecules” . If so, using what technology you actually observed those “hidden molecules”? Could you find the drug molecules lying hidden in each and every fractions of ultra dilutions?
You have said that “some alterations in hydrogen bond structure can be detected” in potentized drugs. How could you jump into the conclusion that these “alterations” are indications of “hidden” drug molecules? If ‘alterations’ could be seen in the ‘whole’ volume of potentized drugs, it is sure that it will not be due to “hidden” molecules, which even if present, will not be enough in numberst to be distributed in every part of the potentized drugs. Why cant you think these “alterations of hydrogen bonds” may be due to a rearrangement of water-ethyl alcohol molecules at their supra-molecular level, which indicates ‘molecular imprinting’?
2. My point was, ‘chemical constitution’ of plain water-alcohol mixture and ‘high potency drugs’ will be the same., since both will contain only water and ethyl alcohol molecules. I agree with your statement “both solutions possess much difference in their crystal water properties, detectable by Fourier Transform Infra Red spectrophotometer”. Difference in “rystal water properties” do not indicate any difference in their “elemental constitution”. On the other hand, it is a clear evidence for supra-molecular rearrangement of vehicle happening during potentization, which points to ‘molecular imprinting’.
3. If the therapeutic actions of high potencies were due to the “drug molecules remaining hidden within the cluster of solvent molecules”, It is very obvious that WHOLE volume of a given dilution will not be therapeutically effective. Homeopaths know very well that they get curative effects from using each and every minute fractions of a given volume of high potency drug. Anybody who knows there is a limitation for number of molecules in a given quantity of any substance knows very well that ‘drug molecules’ will not be present ‘everywhere’, even after diluting the substance millions of times!
4. There have been a lot published research reports demonstrating the difference in spectro-photometric studies of ultra dilution drugs and plain water-alcohol mixtures. Such a difference is an obvious indication for supra-molecular rearrangement happening due to ‘molecular imprinting.
5. Of course, sir. We already have a lot of in vitro and in vivo scientific studies to show “high potency drugs have biological properties that are reverse to those of their molecular forms”. I can provide reference links if you want.
6. Exact molecular mechanism of phenomenon of so called “hormesis” is still unexplained scientifically. Concept of hormesis is applicable only in effects of “small quantities” of toxic substances. It has no any relevance in homeopathic ultra dilution effects, which will not contain any ‘quantity’ of drug substance. I can give you reference links of scientific studies which prove ” high potency drugs are capable of antidoting or neutralizing the biological effects of molecular forms of same drugs”.
READ THIS FOLLOWING ARTICLE FOR THE REFERENCES I MADE IN ABOVE POINTS :
‘Analysis Of Some Important Scientific Studies That Indirectly Validates MIT Concepts’
Click to access analysis-of-studies.pdf
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I do agree with your opinion that a hypothesis should be erected from the available data before experimenting anything. However, I have something to comment on your opinion of ‘molecular imprinting’ concept:
1. If ‘molecular imprinting’ concept is right, there will not any single ‘molecule’ of original drug substance remaining in potencies above avogadro limit, if they are genuinely potentized.
Ans: Presence of single molecule cannot be proved even by most sophisticated spectrophotometer. Even radio-immuno assay methods have some limitations. In ultra low dilution the solute molecules remain so tightly entrapped by solvent molecules that the ordinary spectrophotometric data cannot reveal their existence. Only some alterations in hydrogen bond structure can be detected.
2. If ‘molecular imprinting’ concept is right, chemical analysis of high potency drugs and plain water-alcohol mixture will prove they have same chemical constitution.
Ans: Experimentally it has been proved that it does not occur. Both solutions possess much difference in their crystal water properties, detectable by Fourier Transform Infra Red spectrophotometer. It can sense alteration of hydrogen bond structures, which are specific for each drug. However, the detection of drug molecule (only applicable for drugs of mineral origin) requires Atomic absorption spectrophotometry and electron microscopic study, which the team actually did.
3. If ‘molecular imprinting’ concept is right, potentized drugs have therapeutic effects if used as per indications, but plain water-alcohol mixture will not exhibit any therapeutic effect.
Ans: If drug molecules remain hidden within the cluster of solvent molecule they can move interior of a cell and stimulate the minute proteins. In case of simple water-alcohol mixture it is not possible.
4. If ‘molecular imprinting’ concept is right, spectrometric studies will show that high potency drugs and plain water-alcohol mixtures are entirely different in their supra-molecular organizations.
Ans: There is a limitation of ordinary spectrophotometric data. It cannot sense element below a limit of detection. Also solvent-masked drug molecules remain hidden from the exposure of ordinary spectrophotometer, though it can be detected to some extent by atomic absorption spectrophotometer, because it burns away its solvent shield by acetylene flame.
5. If ‘molecular imprinting’ concept is right, in vitro and in vivo studies will prove that high potency drugs have biological properties that are reverse to those of their molecular forms (below 12c)
Ans: Certainly. Do you see any noticeable difference between Nux vom 6c and Nux vom 30c in curing the patients?
6. If ‘molecular imprinting’ concept is right, high potency drugs should be capable of antidoting or neutralizing the biological effects of molecular forms of same drugs.
Ans: There are so many evidences that prove that pre or post treatment of minute dose drugs (molecular or non-molecular) can decrease or nullify the effect of higher dose drugs. The best known example is Hormesis.
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