REDEFINING HOMEOPATHY

Chandran K C Explains Homeopathy As Molecular Imprints Therapeutics (MIT)

Scope And Limitations Of Homeopathy In Genetic Disorders


A question frequently asked by homeopaths is, whether potentized homeopathic medicines can CURE ‘genetic disorders’.

A ‘genetic disorder’ is an illness caused by abnormalities in genes or chromosomes, especially a condition that is present from before birth. Most genetic disorders are quite rare and affect one person in every several thousands or millions.

A ‘genetic disorder’ may or may not be a heritable disorder. Some genetic disorders are passed down from the parents’ genes, but others are always or almost always caused by new mutations or changes to the DNA. In other cases, the same disease, such as some forms of cancer, may be caused by an inherited genetic condition in some people, by new mutations in other people, and by nongenetic causes in still other people.

Diseases arising from ‘inherited’ genetic abnormalities cannot be CURED by homeopathy.

Diseases caused by ‘ new mutations or changes to the DNA’ could be ‘prevented’, cured, or at least ‘relieved’ by homeopathic treatment.

Potentized drugs cannot create epigenetic errors, but can prevent it, and deal with pathologies arising from epigenetic causes

In any genetic disorders, there would be a cascading of molecular errors, which are caused by the absence of abnormality of some essential proteins or enzymes. Secondary diseases arising from such cascading actions resulting from genetic disorders could be treated by homeopathy, even though the basic abnormality of genes will remain untouched by such a treatment. We can say, we cannot CURE genetic disorders, but can give relief to many complaints associated with such disorders.

Possibilities of potentized homeopathic medicines interacting with genetic substance in the organism is a subject of much concern, speculations and controversy among homeopaths. Such controversies arise from the lack of sufficient understanding regarding the active principles contained in potentized medicines, and their exact mechanism of action in the living system.
With our new scientific understanding of potentization as a process of molecular imprinting, we are now in a better position to answer these questions satisfactorily. Since, molecular imprints contained in the potentized homeopathic preparations cannot successfully compete with natural ligands in binding with their target molecules, there is no possibility of potentized homeopathic medicines producing any effect on  genetic material that may result in mutations.

Molecular imprints contained in the potentized homeopathic preparations bind to ligands or biological molecules merely due to their complementary configurations without any charge affinity, whereas natural ligands bind to their biological target molecules in capacity of their appropriate spacial configurations as well as charge affinities. So, the bindings of molecular imprints with biological molecules or their ligands will be very temporary and cannot stay long. Such bindings of molecular imprints cannot replace the natural ligand-target interactions happening as part of vital processes.

Molecular imprints can not compete with natural ligands in binding to their natural biological targets. Hence it is obvious that potentized homeopathic preparations cannot interfere in biological ‘ligand-target’ processes such as ‘substrate-enzyme’, ‘antigens-antibodies’, ‘signal-receptor’ etc. As such, chances of potentized homeopathic medicines acting as pathological agents are very rare even if used indiscriminately. Molecular imprints can interfere only in interactions between pathogenic molecules and biological molecules, as well as off-target bindings of ligands with biological molecules, where only configurational affinity is involved. Obviously, molecular imprints can act upon only the molecular blocks created by exogenous or endogenous foreign pathological molecules.

At the same time, these molecular imprints can effectively deal with the pathogenic actions of deformed proteins that may result from genetic errors, thereby preventing them from creating cascading of pathological molecular blocks at various targets. As such, homeopathic medicines can play a great role even in the treatment of certain diseases of genetic origin, at least as palliatives.

More over, potentized homeopathic medicines can safeguard genetic material from dangerous mutations that may be caused the by inhibitory actions of endogenous or exogenous pathogenicl agents such as toxic drugs, heavy metals, super-oxides etc., on enzymes related with nucleic acid synthesis and genetic expressions.

3 Comments

  1. The belief that all homeopathic medicines are non-molecular is not beyond question (vide ‘Thermo-Luminescence Studies Of Ultra-high Dilutions’ Provides Proof For ‘Molecular Imprinting’). Furthermore, the idea that ‘non-molecular solution cannot transmit signal’ is no more a valid theory. The concept of hormesis is very similar to ‘ isopathy ‘, a forerunner branch of homeopathy. The first remedy introduced in homeopathy was an isopathic one. The curative power of Peruvian bark (Cinchona) in treating marsh-ague (Malaria) was known during Hahnemann’s time. In spite of that, some patients after the cure of malaria frequently developed some toxicological symptoms, such as intermittent shivering fever and attacks of various other disorders like trembling of limbs etc. The symptoms were observed even in healthy persons after treating the same drug. Hahnemann thus discovered the first homeopathic remedy ‘China’ from the same plant in minute dose to treat the Cinchona related toxicological symptoms according to the principle of isopathy. Later, he discovered the efficacy of potentizing the medicine to increase its curative power several fold, because it increases penetration power of the remedy. There are several examples of isopathic use of homeopathic drugs. Fisher et al (1987) showed the influence of the homeopathic remedy Plumbum met on the lead excretion kinetics of in rats. Experimental lead acetate treated rats by Begum et al (1994) demonstrated the impairment of Amino Levulinic acid Dehydratase (ALAD) activity in blood and anemia. Some of the experimental rats were isolated and administrated homeopathic drugs “Plumbum” (prepared from lead salt) and “Opium”. They showed significant recovery. There are several similar examples also, where pretreatment doses are much higher, and post treatment doses are minute for the same toxicant that causes recovery in rats. It was seen from the effect of Arsenic (Cazin et al, 1987) in rats.
    Dr Sanjib Chattopadhyay

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  2. According to most of the modern workers, homeopathy is closely related to ‘Hormesis’ , i.e., attainment of tolerance to a poison by minute pretreatment of the same. Hormesis can also be achieved in the opposite way. Effect of heavy metal pollution in affected animals found decreasing by post-treatment of the same or similar metal in minute dose. Thus by the application of low dose of the same damaging agents (viz. “stressors”) exert a stimulatory action on cell culture; it protects them from harmful exposures of the same stress. Homeopathic medicines no matter how minute is it, contain stressors that being ‘penetratingly efficacious’ can bring disease symptoms in healthy persons when applied in higher dose. Conversely, in patients it can decrease the number of incompetent cells in the diseased tissue during the successive generations of cell cycle when applied in minute dose. The genetically most favorable cells in patients that are able to combat with the stress multiply more rapidly than the diseased ones as in clonal selection model. This is equally true for any type of multiplying cells. Even in non-dividing cells, e.g., nerve cells are equally effective to fight with the stressor. It can produce a variety of protein molecules more successfully, called neuropeptides having controlling influence over the synthesis of any type of proteins. Stress can induce multiplication of transposable element over the genome and it was supported by experimental evidences. Thus the diseased DNA segments become outnumbered by the healthy gene, which increases in number by copy and paste method and the medicine shows salutary effect. However, patients having congenital chromosomal or genetic defect involving the whole body cannot be treated pragmatically by homeopathic means. The latter is only possible for dynamic diseases, where there is natural aggravation and amelioration cycle of symptoms; it means the disease involves a large number of dividing cells, or multiple duplicating segments of junk DNA. Thus, the deficiency or malfunction of the respective enzymes is recovered.
    Dr Sanjib Chattopadhyay

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    • Chandran Nambiar

      HORMESIS is all about SMALL DOSES. But homeopathy is about NO-DOSES. Their comparison is inappropriate and illogical

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